St. Baldrick’s Childhood Cancer Research Foundation is joining forces with Stand Up To Cancer (SU2C) and Beast Philanthropy to help raise awareness about the need to fund critical cancer research and create the next SU2C Pediatric Cancer Dream Team.
This campaign will support a collaborative team of scientists working together to tackle some of childhood cancer’s biggest research challenges and develop better treatments for kids. As part of this effort, St. Baldrick’s has committed to raising $1.5 million, continuing our longstanding investment in collaborative childhood cancer research.
A Global Spotlight on Childhood Cancer Research
This effort is receiving global attention through an inspiring new video from MrBeast’s YouTube channel, created in partnership with MrBeast and Beast Philanthropy. With an audience of more than 508 million subscribers, MrBeast is helping bring the urgent need for childhood cancer research to millions of people around the world.
In the video, Jimmy Donaldson (MrBeast) grants 100 wishes for kids with cancer, creating moments of joy and hope for children and their families. Several St. Baldrick’s Honored Kids were featured, giving our community the opportunity to be part of this meaningful effort.
But the video reveals an even bigger wish shared by families everywhere: cures for all childhood cancers.
The video also announces a new collaboration between Beast Philanthropy, Stand Up To Cancer and St. Baldrick’s to help create the next SU2C Pediatric Cancer Dream Team and together find cures.

In MrBeast’s video, “I Helped 100 Kids Fight Cancer,” MrBeast and NBA star LeBron James surprised six local St. Baldrick’s Honored Kids and other pediatric cancer survivors at the LeBron James Family Foundation’s I PROMISE School in Akron, Ohio, with the experience of a lifetime. Photo courtesy of the LeBron James Family Foundation.
What Is a SU2C Pediatric Cancer Dream Team?
A SU2C Dream Team is a collaborative research project that brings together leading scientists, clinicians, and institutions to tackle complex childhood cancer challenges.
Rather than working in separate labs, researchers work together—sharing data, expertise, and discoveries in real time. By combining different perspectives and areas of expertise, they can answer bigger questions and move promising research forward faster.
How Will This New Dream Team Be Chosen?
Before a single research project begins, the right team has to be assembled.
SU2C will issue a nationwide call for research proposals. Scientists and institutions will submit ideas for the next Pediatric Cancer Dream Team, outlining how they would work together to address critical challenges in childhood cancer.
Those proposals will then undergo a rigorous scientific review by a committee of leading pediatric cancer experts and members of Stand Up To Cancer’s Scientific Advisory Committee. As a funding partner, St. Baldrick’s will nominate one representative to serve on the selection committee, helping oversee the review process alongside other experts. Every application is evaluated for scientific excellence, innovation, collaboration, and the potential to improve outcomes for children with cancer.
This process helps ensure that donor dollars support the strongest science and the research with the greatest potential to improve outcomes for kids.
>>>Donate and Make the next Dream Team Possible
Why St. Baldrick’s Continues to Invest in Collaborative Research
In 2013, St. Baldrick’s joined Stand Up To Cancer and other partners to co-fund the first-ever Pediatric Cancer Dream Team through a $14.5 million grant. Following its success, St. Baldrick’s continued supporting the collaboration with $10.8 million in additional funding under its new name, EPICC (Empowering Pediatric Immunotherapies for Childhood Cancer).
Together, those investments helped support 45 clinical trials, treat more than 1,370 children, advance the first FDA-approved gene therapies for childhood cancer, and drive discoveries that are changing how researchers approach blood, brain, and bone cancers.
The results demonstrated what’s possible when researchers unite around a shared goal—and why St. Baldrick’s is helping launch the next SU2C Pediatric Cancer Dream Team.

Learn about the decade of progress made by the original St. Baldrick’s–Stand Up To Cancer Dream Team and how its work continued through the EPICC Team.
A Decade Of EPICC Progress In Kids’ Cancer Research
Help Make the Next Dream Team Possible
The spotlight created by Beast Philanthropy is introducing millions of people to the urgent need for childhood cancer research. But awareness alone won’t change the future for kids with cancer. Research requires sustained investment, collaboration, and a community committed to making progress possible.
St. Baldrick’s is working to raise $1.5 million toward this campaign, helping lay the foundation for the next Pediatric Cancer Dream Team and the discoveries that follow.
Together with Stand Up To Cancer, Beast Philanthropy, researchers, and supporters around the world, we’re investing in the ideas that could change childhood cancer treatment for generations to come.
Join us in helping make the next Pediatric Cancer Dream Team possible. Every gift brings us one step closer to funding the research that gives kids with cancer the brighter future they deserve.
Help Create the Next Dream Team



LeBron gave MrBeast the keys to his Foundation’s House Three Thirty, a one-of-a-kind destination designed to bring the community together and big dreams to life in Akron. There, MrBeast and St. Baldrick’s Honored Kids engaged in fun-filled activities, finishing up with an inspiring tour of the world’s only LeBron James museum and a memorable family meal at Buckets. Photos courtesy of the LeBron James Family Foundation.
Frequently Asked Questions
What is the SU2C Pediatric Cancer Dream Team?
The SU2C Pediatric Cancer Dream Team is a collaborative research project led by Stand Up To Cancer that brings together leading scientists and institutions to tackle some of the biggest challenges in childhood cancer and accelerate progress toward better treatments.
Is St. Baldrick’s part of Stand Up To Cancer?
No. St. Baldrick’s is an independent nonprofit and the largest charity funder of childhood cancer research grants in the U.S. For more than 25 years, St. Baldrick’s has invested in research at leading institutions across the U.S. and beyond, funding studies across all childhood cancers and every stage of research—from early discoveries in the lab to clinical trials that bring new treatments closer to kids who need them. In this campaign, St. Baldrick’s is collaborating with Stand Up To Cancer, Beast Philanthropy, and other partners to help fund the launch of the next SU2C Pediatric Cancer Dream Team.
How is St. Baldrick’s involved?
St. Baldrick’s has committed to raising $1.5 million toward this campaign to help raise awareness about the need to fund critical cancer research and launch the next SU2C Pediatric Cancer Dream Team, continuing more than 25 years of investment in childhood cancer research.
How will the next Pediatric Cancer Dream Team be selected?
Stand Up To Cancer will invite researchers to submit proposals for consideration. Applications will undergo a rigorous scientific review by leading pediatric cancer experts to ensure funding supports the most promising research and areas of greatest need.
What is collaborative childhood cancer research?
Collaborative research brings together experts from multiple institutions to share knowledge, data, and discoveries, helping accelerate progress toward better treatments for children with cancer.
Has St. Baldrick’s funded this type of research before?
Yes. In 2013, St. Baldrick’s co-funded the first Pediatric Cancer Dream Team and later continued supporting the collaboration through EPICC (Empowering Pediatric Immunotherapies for Childhood Cancer).
