Eleanor Chen, M.D., Ph.D., a St. Baldrick’s Scholar, shares insights into Embryonal Rhabdomyosarcoma (ERMS): its symptoms, treatment options, and the critical need for ongoing research.
What is Embryonal Rhabdomyosarcoma?
Embryonal Rhabdomyosarcoma (ERMS) is a rare type of soft tissue cancer that originates from embryonic skeletal muscle tissue, which typically forms skeletal muscles like those in the arms and legs. However, ERMS often starts in other areas such as the head, neck, bladder, or reproductive organs, rather than the limbs.
Signs and Symptoms of Embryonal Rhabdomyosarcoma
The symptoms of ERMS depend on the location of the tumor. A rapidly growing tumor often causes noticeable issues, such as:
- Nose or Sinuses: Nosebleeds or sinus congestion.
- Eye Area: Blurry vision or bulging of the eye.
- Bladder: Difficulty urinating due to obstruction caused by the tumor.
- Abdomen: Pain, vomiting, or constipation.
If your child is experiencing any of these symptoms, consult a doctor immediately for proper evaluation. Early diagnosis is critical.
Treatment Options for Embryonal Rhabdomyosarcoma
Treatment for ERMS typically involves a combination of therapies, including:
- Chemotherapy to shrink or kill cancer cells.
- Surgery to remove the tumor.
- Radiation therapy to target remaining cancer cells.
These treatments can be very effective, especially if the cancer is detected early.
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Current Research and Challenges
Thanks to advances in treatment, about 80% of children with Embryonal Rhabdomyosarcoma survive when diagnosed early and treated properly. However, survival rates drop significantly if the cancer returns or spreads to other parts of the body.
Unfortunately, there are currently no effective targeted therapies for children with recurrent or metastatic ERMS. More research is urgently needed to understand why these tumors spread and return, and to develop new, more effective treatment options.
How You Can Help
Children with Embryonal Rhabdomyosarcoma need your support. By donating, you can help fund groundbreaking research to improve survival rates and discover better treatments for kids battling this rare cancer.
Donate now to help kids with cancer.
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Learn about one of our recent Research Outcomes dealing with Embryonal Rhabdomyosarcoma:
Research Outcomes: Fighting Cancer & Helping Survivors
